Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88.

The filamentous fungus Aspergillus niger exhibits great diversity in its phenotype. It is found globally, both as marine and terrestrial strains, produces both organic acids and hydrolytic enzymes in high amounts, and some isolates exhibit pathogenicity. Although the genome of an industrial enzyme-producing A. niger strain (CBS 513.88) has already been sequenced, the versatility and diversity o...

Citric Acid Production by Aspergillus Niger*

the Stokes' equation (4). The anomalous appearance of the curves might suggest that a non-random sample had been selected, but examination of the frequencies of cells appearing in different size ranges reveals a normal distribution indicating that a random sample had been selected. The diameters of cells and the correspondent frequencies are: 3.5-2; 4.0-7; 4.5-10; 5.0-20; 5.5-17; 6.0-8; 6.5-2; ...

Production of citric acid by mutants of Aspergillus niger.

Development of methodology for the recovery of citric acid from the fermented broth involves standardization of the various parameters to achieve maximum performance in terms of recovery and optimum conditions. The present investigation was carried out to study the purification of citric acid from fermented broth by calcium carbonate precipitation and subsequent acid hydrolysis. The parameters ...

High-potency Amyloglucosidase-producing Mold of the Aspergillus Niger Group.

Aconitase and citric acid fermentation by Aspergillus niger.

In view of the often-cited theory that citric acid accumulation is caused by an inhibition of aconitase activity, the equilibrium of the reaction of aconitase was investigated by comparing in vivo steady-state concentrations of citrate and isocitrate in Aspergillus niger grown under various citric acid-producing conditions. With the equilibrium catalyzed by the A. niger enzyme in vitro, similar...